Activity record

PGDB_A007288

Assay: viabilityTarget: GSPT1QC: ambiguous
Activity overview

IC50 = 20.27 nM

TargetGSPT1
Cell lineSK-BR-3
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001340
PatentWO2025252247A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005465
Compound IDPGDB_C005465
Compound化合物11;实施例 11;实施例 11
Source record IDPGDB_C005465
InChIKeyYKUVWBCFXJBHCA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001340
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineSK-BR-3

Source evidence

Patent IDWO2025252247A1
Compound location

化合物11;实施例 11;实施例 11

化合物11;实施例 11;实施例 11 enlarged structure化合物11;实施例 11;实施例 11 location on patent page 61
Activity table
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