Activity record

PGDB_A007528

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

DC50 = 32 nM

TargetIKZF1
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000591
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010131
Compound IDPGDB_C010131
Compound2
Source record IDPGDB_C010131
InChIKeySTBPHXSTASSXPE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000591
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetIKZF1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

2

2 enlarged structure2 location on patent page 78
Activity table
Page 94 · table single