Activity record

PGDB_A007937

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

EC50 = 100-1000 nM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS000488
PatentWO2025024521A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020445
Compound IDPGDB_C020445
Compound272
Source record IDPGDB_C016575
InChIKeySWVJPMBPKVLTAJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000488
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

272

272 enlarged structure272 location on patent page 88
Activity table
Page 416 · table start
Page 417 · table middle
Page 418 · table end