Activity record

PGDB_A008030

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 < 1 uM

TargetCRBN
E3 ligaseCRBN
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001252
PatentWO2022066835A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019578
Compound IDPGDB_C019578
Compound11;11
Source record IDPGDB_C001371
InChIKeyIKDVSFZRINDHDU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001252
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022066835A1
Compound location

11;11

11;11 enlarged structure11;11 location on patent page 171
Activity table
Page 165 · table single