Activity record

PGDB_A008067

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 26 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001553
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020455
Compound IDPGDB_C020455
Compound282
Source record IDPGDB_C016303
InChIKeyADJJKXDCGHJFRR-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001553
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

282

282 enlarged structure282 location on patent page 88
Activity table
Page 416 · table single