Activity record

PGDB_A008079

Assay: % DegradationTarget: SALL4QC: standardized
Activity overview

DC50 = 0.332 uM

TargetSALL4
Cell lineHT-1080
Time20 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001426
PatentWO2023025136A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009601
Compound IDPGDB_C009601
Compound泊马度胺
Source record IDPGDB_C000056
InChIKeyUVSMNLNDYGZFPF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001426
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time20 h
TargetSALL4
E3Not specified
Cell lineHT-1080
OrganismHomo sapiens

Source evidence

Patent IDWO2023025136A1
Compound location

泊马度胺

泊马度胺 enlarged structure泊马度胺 location on patent page 81
Activity table
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