Activity record

PGDB_A008091

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

inhibition = 99.15 %

TargetGSPT1
Cell lineNCI-H526
Time3 d
Assay / Readoutluminescence / % Inhibition
Assay IDPGDB_AS000350
PatentWO2023001028A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001868
Compound IDPGDB_C001868
CompoundWX016
Source record IDPGDB_C001868
InChIKeyUSEQRCHYCVHABT-GOSISDBHSA-N

Assay context

Assay IDPGDB_AS000350
Assay familyviability
Assay systemcell_based
Readout% Inhibition
Technologyluminescence
Treatment time3 d
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H526

Source evidence

Patent IDWO2023001028A1
Compound location

WX016

WX016 enlarged structureWX016 location on patent page 39
Activity table
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