Loading compound
Loading detail record from the SQLite release...
Compound
PGDB_C001868
8 activity records1 related patents
2D structure
COCCOc1cc(NC(=O)NCc2ccc3c([C@H]4CCC(=O)NC4=O)coc3c2)cc(Cl)c1CCompound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| % Inhibition | - | = | 99.15 | % | - | 3 d | GSPT1 | - | NCI-H526 | WO2023001028A1 | PGDB_A008091 | PGDB_C001868 | PGDB_AS000350 | View |
| % Inhibition | - | = | 92.76 | % | - | 3 d | GSPT1 | - | NCI-H1581 | WO2023001028A1 | PGDB_A025933 | PGDB_C001868 | PGDB_AS000288 | View |
| IC50 | - | = | 0.1 | nM | - | — | GSPT1 | - | NCI-H526 | WO2023001028A1 | PGDB_A031193 | PGDB_C001868 | PGDB_AS001706 | View |
| % Inhibition | - | = | 69.31 | % | - | 3 d | GSPT1 | - | NCI-H69 | WO2023001028A1 | PGDB_A033798 | PGDB_C001868 | PGDB_AS002018 | View |
| IC50 | - | = | 5.9 | nM | - | — | GSPT1 | - | NCI-H1581 | WO2023001028A1 | PGDB_A040421 | PGDB_C001868 | PGDB_AS000790 | View |
| IC50 | - | = | 6.5 | nM | - | — | GSPT1 | - | NCI-H69 | WO2023001028A1 | PGDB_A047056 | PGDB_C001868 | PGDB_AS001964 | View |
| IC50 | - | = | 5.8 | nM | - | — | GSPT1 | - | DMS114 | WO2023001028A1 | PGDB_A052286 | PGDB_C001868 | PGDB_AS000425 | View |
| % Inhibition | - | = | 91.27 | % | - | 3 d | GSPT1 | - | DMS114 | WO2023001028A1 | PGDB_A059462 | PGDB_C001868 | PGDB_AS001771 | View |