Activity record

PGDB_A008888

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 11.6 nM

TargetGSPT1
Cell lineHL-60
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002047
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005331
Compound IDPGDB_C005331
Compound4-151;4-151;4-151
Source record IDPGDB_C005331
InChIKeyPTBVVYNCCQMWTN-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002047
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023078410A1
Compound location

4-151;4-151;4-151

4-151;4-151;4-151 enlarged structure4-151;4-151;4-151 location on patent page 6
Activity table
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