Assay

PGDB_AS002047

System: cell_basedCell line: HL-60
Assay context summary

Assay context

23 activity records
Assay familyviability
Systemcell_based
ReadoutIC50
E3Not specified
Cell lineHL-60
Technologyluminescence
Detection targetcell_proliferation
Activity compounds and values

Activity records

23 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C005331
IC50-=11.6nM-—GSPT1-HL-60WO2023078410A1PGDB_A008888PGDB_C005331PGDB_AS002047View
2D structure for PGDB_C005327
IC50-=14.3nM-—GSPT1-HL-60WO2023078410A1PGDB_A010274PGDB_C005327PGDB_AS002047View
2D structure for PGDB_C005309
IC50-=5nM-—GSPT1-HL-60WO2023078410A1PGDB_A018693PGDB_C005309PGDB_AS002047View
2D structure for PGDB_C005359
IC50-=4.6nM-—GSPT1-HL-60WO2023078410A1PGDB_A019545PGDB_C005359PGDB_AS002047View
2D structure for PGDB_C005310
IC50-=6.9nM-—GSPT1-HL-60WO2023078410A1PGDB_A020165PGDB_C005310PGDB_AS002047View
2D structure for PGDB_C005353
IC50-=12.8nM-—GSPT1-HL-60WO2023078410A1PGDB_A025897PGDB_C005353PGDB_AS002047View
2D structure for PGDB_C005355
IC50-=18.6nM-—GSPT1-HL-60WO2023078410A1PGDB_A027253PGDB_C005355PGDB_AS002047View
2D structure for PGDB_C005301
IC50-=25.8nM-—GSPT1-HL-60WO2023078410A1PGDB_A030536PGDB_C005301PGDB_AS002047View
2D structure for PGDB_C005337
IC50-=37.7nM-—GSPT1-HL-60WO2023078410A1PGDB_A031835PGDB_C005337PGDB_AS002047View
2D structure for PGDB_C005340
IC50-=35.4nM-—GSPT1-HL-60WO2023078410A1PGDB_A031841PGDB_C005340PGDB_AS002047View
2D structure for PGDB_C005352
IC50-=25.2nM-—GSPT1-HL-60WO2023078410A1PGDB_A034636PGDB_C005352PGDB_AS002047View
2D structure for PGDB_C005354
IC50-=11nM-—GSPT1-HL-60WO2023078410A1PGDB_A035326PGDB_C005354PGDB_AS002047View
2D structure for PGDB_C005303
IC50-=8.3nM-—GSPT1-HL-60WO2023078410A1PGDB_A035587PGDB_C005303PGDB_AS002047View
2D structure for PGDB_C005330
IC50-=12.4nM-—GSPT1-HL-60WO2023078410A1PGDB_A040294PGDB_C005330PGDB_AS002047View
2D structure for PGDB_C005326
IC50-=15nM-—GSPT1-HL-60WO2023078410A1PGDB_A041147PGDB_C005326PGDB_AS002047View
2D structure for PGDB_C005306
IC50-=12.8nM-—GSPT1-HL-60WO2023078410A1PGDB_A044402PGDB_C005306PGDB_AS002047View
2D structure for PGDB_C005308
IC50-=14.3nM-—GSPT1-HL-60WO2023078410A1PGDB_A046174PGDB_C005308PGDB_AS002047View
2D structure for PGDB_C005329
IC50-=4.2nM-—GSPT1-HL-60WO2023078410A1PGDB_A056470PGDB_C005329PGDB_AS002047View
2D structure for PGDB_C005333
IC50-=12.5nM-—GSPT1-HL-60WO2023078410A1PGDB_A061811PGDB_C005333PGDB_AS002047View
2D structure for PGDB_C005304
IC50-=9.2nM-—GSPT1-HL-60WO2023078410A1PGDB_A064867PGDB_C005304PGDB_AS002047View
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