Activity record

PGDB_A009050

Assay: % DegradationTarget: CSNK1A1QC: standardized
Activity overview

DC50 < 10 nM

TargetCSNK1A1
Cell lineMV-4-11
Time16 h
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS001026
PatentCN121471230A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001054
Compound IDPGDB_C001054
Compound10;10;实施例10
Source record IDPGDB_C001054
InChIKeyMAPABXAOAUIBEW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001026
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
Treatment time16 h
Detection targetprotein_degradation
TargetCSNK1A1
E3Not specified
Cell lineMV-4-11

Source evidence

Patent IDCN121471230A
Compound location

10;10;实施例10

10;10;实施例10 enlarged structure10;10;实施例10 location on patent page 5
Activity table
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