Activity record

PGDB_A009182

Assay: biochemicalTarget: CTNNB1QC: ambiguous
Activity overview

EC50 < 1 uM

TargetCTNNB1
E3 ligaseBTRC | FBXW11
Time1 h
Assay / ReadoutEC50 / biochemical
Assay IDPGDB_AS000640
PatentWO2025179005A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C021142
Compound IDPGDB_C021142
Compound237
Source record IDPGDB_C021142
InChIKeyJPBUSVOONAVICO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000640
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
Treatment time1 h
TargetBTRC | FBXW11 | SKP1
E3BTRC | FBXW11 | SKP1

Source evidence

Patent IDWO2025179005A1
Compound location

237

237 enlarged structure237 location on patent page 549
Activity table
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