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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A009524

Assay: % DegradationTarget: WIZQC: standardized

Activity overview

Dmax = 81.2 %

TargetWIZ

Cell lineHT-1080

ConcentrationConcentration series: 10 uM, 0.316 nM

Time20 h

Assay / Readoutluminescence / Dmax

Assay IDPGDB_AS002062

PatentWO2025256460A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C012067

Compound31

Source record IDPGDB_C012067

InChIKeyRWZVSUQFGMNXJJ-NRFANRHFSA-N

Assay context

Assay IDPGDB_AS002062

Assay family% Degradation

Assay systemcell_based

ReadoutDmax

Technologyluminescence

ConcentrationConcentration series: 10 uM, 0.316 nM

Treatment time20 h

TargetWIZ | GSPT1

E3Not specified

Cell lineHT-1080

OrganismHomo sapiens

Source evidence

Patent IDWO2025256460A1

Compound location

31

31 enlarged structure

31 location on patent page 93

Activity table

Page 163 · table start

Page 164 · table middle

Page 165 · table middle

Page 166 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU