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Patent
WO2025256460A1
115 compounds237 activity records4 assays
Patent summary
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | DC50 | - | = | 16.6 | nM | - | — | WIZ | - | HT-1080 | PGDB_A007034 | PGDB_C012089 | PGDB_AS000508 | View |
 | DC50 | - | = | 44.1 | nM | - | — | WIZ | - | HT-1080 | PGDB_A007446 | PGDB_C012145 | PGDB_AS000508 | View |
 | Dmax | - | = | 88.5 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A007840 | PGDB_C012144 | PGDB_AS002062 | View |
 | Dmax | - | = | 92.4 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A007904 | PGDB_C012093 | PGDB_AS002062 | View |
 | Dmax | - | = | 88.9 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A008226 | PGDB_C012053 | PGDB_AS002062 | View |
 | DC50 | - | = | 10.3 | nM | - | — | WIZ | - | HT-1080 | PGDB_A008228 | PGDB_C012090 | PGDB_AS000508 | View |
 | DC50 | - | = | 11.9 | nM | - | — | WIZ | - | HT-1080 | PGDB_A008330 | PGDB_C012106 | PGDB_AS000508 | View |
 | Dmax | - | = | 90.9 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A008761 | PGDB_C012074 | PGDB_AS002062 | View |
 | Dmax | - | = | 93.5 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A008834 | PGDB_C012127 | PGDB_AS002062 | View |
 | Dmax | - | = | 81.2 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A009524 | PGDB_C012067 | PGDB_AS002062 | View |
 | Dmax | - | = | 92.2 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A009686 | PGDB_C012056 | PGDB_AS002062 | View |
 | Dmax | - | = | 87.7 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A010135 | PGDB_C012141 | PGDB_AS002062 | View |
 | Dmax | - | = | 91.3 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A010284 | PGDB_C012077 | PGDB_AS002062 | View |
 | Dmax | - | = | 89.1 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A010328 | PGDB_C012159 | PGDB_AS002062 | View |
 | DC50 | - | = | 23.8 | nM | - | — | WIZ | - | HT-1080 | PGDB_A010414 | PGDB_C012120 | PGDB_AS000508 | View |
 | Dmax | - | = | 92 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A010751 | PGDB_C012110 | PGDB_AS002062 | View |
 | DC50 | - | = | 7.2 | nM | - | — | WIZ | - | HT-1080 | PGDB_A010941 | PGDB_C012150 | PGDB_AS000508 | View |
 | Dmax | - | = | 92.9 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A011068 | PGDB_C012116 | PGDB_AS002062 | View |
 | DC50 | - | = | 40.2 | nM | - | — | WIZ | - | HT-1080 | PGDB_A011136 | PGDB_C012151 | PGDB_AS000508 | View |
 | Dmax | - | = | 79.5 | % | Concentration series: 10 uM, 0.316 nM | 20 h | WIZ | - | HT-1080 | PGDB_A011238 | PGDB_C012073 | PGDB_AS002062 | View |