Activity record

PGDB_A009577

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 2.15 uM

TargetCRBN
E3 ligaseCRBN
Time3 h
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000788
PatentWO2023151635A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001192
Compound IDPGDB_C001192
CompoundGT-03259
Source record IDPGDB_C001192
InChIKeyZHLSTGYFPJVVFP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000788
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time3 h
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDWO2023151635A1
Compound location

GT-03259

GT-03259 enlarged structureGT-03259 location on patent page 285
Activity table
Page 358 · table single