PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2023151635A1

AssigneeGluetacs Therapeutics Shanghai

TitleCompounds based on quinazoline-substituted glutarimide skeletons and their applications

Family ID87563676

Family members6

Filing year2023

Publication date2026-02-27

JurisdictionWO

Compounds51

Activity records97

Assays8

Activity compounds and values

Activity records

97 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	1653.2	nM	-	—	-	-	Daudi	PGDB_A007197	PGDB_C008731	PGDB_AS000279	View
IC50	-	=	2.52	uM	-	—	CRBN	CRBN	-	PGDB_A007606	PGDB_C001187	PGDB_AS000788	View
IC50	-	=	311.5	nM	-	—	-	-	TMD8	PGDB_A008052	PGDB_C001171	PGDB_AS000648	View
IC50	-	=	1.07	uM	-	—	CRBN	CRBN	-	PGDB_A008767	PGDB_C008731	PGDB_AS000788	View
IC50	-	=	204	nM	-	—	-	-	TMD8	PGDB_A008872	PGDB_C001157	PGDB_AS000648	View
IC50	-	=	1.72	uM	-	—	CRBN	CRBN	-	PGDB_A009503	PGDB_C001158	PGDB_AS000788	View
IC50	-	=	2.15	uM	-	—	CRBN	CRBN	-	PGDB_A009577	PGDB_C001192	PGDB_AS000788	View
IC50	-	=	12.7	nM	-	—	-	-	MM.1R	PGDB_A009697	PGDB_C001156	PGDB_AS001111	View
IC50	-	=	3.3	nM	-	—	-	-	MM.1S	PGDB_A009990	PGDB_C001162	PGDB_AS002383	View
IC50	-	=	309.4	nM	-	—	-	-	TMD8	PGDB_A010574	PGDB_C001166	PGDB_AS000648	View
IC50	-	=	2.8	uM	-	—	CRBN	CRBN	-	PGDB_A010624	PGDB_C001169	PGDB_AS000788	View
IC50	-	=	44.9	nM	-	—	-	-	Daudi	PGDB_A011353	PGDB_C001156	PGDB_AS000279	View
IC50	-	=	2.75	uM	-	—	CRBN	CRBN	-	PGDB_A011457	PGDB_C001193	PGDB_AS000788	View
IC50	-	=	8.2	nM	-	—	-	-	TMD8	PGDB_A012863	PGDB_C001162	PGDB_AS000648	View
IC50	-	=	1.84	uM	-	—	CRBN	CRBN	-	PGDB_A013067	PGDB_C002026	PGDB_AS000788	View
IC50	-	=	86.5	nM	-	—	-	-	TMD8	PGDB_A013204	PGDB_C001156	PGDB_AS000648	View
IC50	-	=	32.8	nM	-	—	-	-	MM.1R	PGDB_A015334	PGDB_C001158	PGDB_AS001111	View
IC50	-	=	1	uM	-	—	CRBN	CRBN	-	PGDB_A016244	PGDB_C001201	PGDB_AS000788	View
IC50	-	=	553.6	nM	-	—	-	-	TMD8	PGDB_A016697	PGDB_C001160	PGDB_AS000648	View
IC50	-	=	285.6	nM	-	—	-	-	Daudi	PGDB_A017902	PGDB_C001157	PGDB_AS000279	View

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