Assay

PGDB_AS000788

System: biochemicalTarget: CRBN
Assay context summary

Assay context

40 activity records
Assay familybiochemical
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
OrganismHomo sapiens
TechnologyHTRF
Activity compounds and values

Activity records

40 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C001187
IC50-=2.52uM-—CRBNCRBN-WO2023151635A1PGDB_A007606PGDB_C001187PGDB_AS000788View
2D structure for PGDB_C008731
IC50-=1.07uM-—CRBNCRBN-WO2023151635A1PGDB_A008767PGDB_C008731PGDB_AS000788View
2D structure for PGDB_C001158
IC50-=1.72uM-—CRBNCRBN-WO2023151635A1PGDB_A009503PGDB_C001158PGDB_AS000788View
2D structure for PGDB_C001192
IC50-=2.15uM-—CRBNCRBN-WO2023151635A1PGDB_A009577PGDB_C001192PGDB_AS000788View
2D structure for PGDB_C001169
IC50-=2.8uM-—CRBNCRBN-WO2023151635A1PGDB_A010624PGDB_C001169PGDB_AS000788View
2D structure for PGDB_C001193
IC50-=2.75uM-—CRBNCRBN-WO2023151635A1PGDB_A011457PGDB_C001193PGDB_AS000788View
2D structure for PGDB_C002026
IC50-=1.84uM-—CRBNCRBN-WO2023151635A1PGDB_A013067PGDB_C002026PGDB_AS000788View
2D structure for PGDB_C001201
IC50-=1uM-—CRBNCRBN-WO2023151635A1PGDB_A016244PGDB_C001201PGDB_AS000788View
2D structure for PGDB_C001164
IC50-=0.32uM-—CRBNCRBN-WO2023151635A1PGDB_A017967PGDB_C001164PGDB_AS000788View
2D structure for PGDB_C001190
IC50-=3.58uM-—CRBNCRBN-WO2023151635A1PGDB_A021272PGDB_C001190PGDB_AS000788View
2D structure for PGDB_C001200
IC50-=1uM-—CRBNCRBN-WO2023151635A1PGDB_A024427PGDB_C001200PGDB_AS000788View
2D structure for PGDB_C001182
IC50-=0.7uM-—CRBNCRBN-WO2023151635A1PGDB_A025187PGDB_C001182PGDB_AS000788View
2D structure for PGDB_C001181
IC50-=2.4uM-—CRBNCRBN-WO2023151635A1PGDB_A030364PGDB_C001181PGDB_AS000788View
2D structure for PGDB_C001170
IC50-=2.61uM-—CRBNCRBN-WO2023151635A1PGDB_A031278PGDB_C001170PGDB_AS000788View
2D structure for PGDB_C001185
IC50-=1.04uM-—CRBNCRBN-WO2023151635A1PGDB_A034216PGDB_C001185PGDB_AS000788View
2D structure for PGDB_C002024
IC50-=2.78uM-—CRBNCRBN-WO2023151635A1PGDB_A034915PGDB_C002024PGDB_AS000788View
2D structure for PGDB_C001163
IC50-=0.46uM-—CRBNCRBN-WO2023151635A1PGDB_A035818PGDB_C001163PGDB_AS000788View
2D structure for PGDB_C001198
IC50-=0.99uM-—CRBNCRBN-WO2023151635A1PGDB_A037721PGDB_C001198PGDB_AS000788View
2D structure for PGDB_C001171
IC50-=0.18uM-—CRBNCRBN-WO2023151635A1PGDB_A039530PGDB_C001171PGDB_AS000788View
2D structure for PGDB_C001191
IC50-=2.24uM-—CRBNCRBN-WO2023151635A1PGDB_A041904PGDB_C001191PGDB_AS000788View
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