Activity record

PGDB_A010068

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 60 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001956
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020453
Compound IDPGDB_C020453
Compound280
Source record IDPGDB_C016301
InChIKeyQYLFVUACMZYNAL-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001956
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

280

280 enlarged structure280 location on patent page 88
Activity table
Page 416 · table single