Activity record

PGDB_A010160

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

IC50 > 100 nM

TargetIKZF1
E3 ligaseCRBN
Cell lineOPM-2
Time5 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001658
PatentAU2019272751B2
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019024
Compound IDPGDB_C019024
CompoundLenalidomide
Source record IDPGDB_C000057
InChIKeyGOTYRUGSSMKFNF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001658
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time5 d
TargetIKZF1
E3CRBN
Cell lineOPM-2

Source evidence

Patent IDAU2019272751B2
Activity table
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