Activity record

PGDB_A010200

Assay: % DegradationTarget: IKZF1QC: ambiguous
Activity overview

degradation = 17.6 %

TargetIKZF1
Concentration100 nM
Assay / Readout% Degradation
Assay IDPGDB_AS000707
PatentWO2024059107A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C002824
Compound IDPGDB_C002824
Compound60;60;60
Source record IDPGDB_C002824
InChIKeyXKHJZGRFJRADNW-ONNFQVAWSA-N

Assay context

Assay IDPGDB_AS000707
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Concentration100 nM
Detection targetprotein_degradation
TargetIKZF1
E3Not specified

Source evidence

Patent IDWO2024059107A1
Compound location

60;60;60

60;60;60 enlarged structure60;60;60 location on patent page 9
Activity table
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