Assay

PGDB_AS000707

System: cell_basedTarget: IKZF1
Assay context summary

Assay context

43 activity records
Assay family% Degradation
Systemcell_based
Readout% Degradation
TargetIKZF1
E3Not specified
Detection targetprotein_degradation
Activity compounds and values

Activity records

43 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C002807
% Degradation-=4.4%100 nM-IKZF1--WO2024059107A1PGDB_A007445PGDB_C002807PGDB_AS000707View
2D structure for PGDB_C002813
% Degradation-=9.3%100 nM-IKZF1--WO2024059107A1PGDB_A008209PGDB_C002813PGDB_AS000707View
2D structure for PGDB_C002824
% Degradation-=17.6%100 nM-IKZF1--WO2024059107A1PGDB_A010200PGDB_C002824PGDB_AS000707View
2D structure for PGDB_C002832
% Degradation-=12.9%100 nM-IKZF1--WO2024059107A1PGDB_A011020PGDB_C002832PGDB_AS000707View
2D structure for PGDB_C002828
% Degradation-=2.4%100 nM-IKZF1--WO2024059107A1PGDB_A013018PGDB_C002828PGDB_AS000707View
2D structure for PGDB_C002827
% Degradation-=6.5%100 nM-IKZF1--WO2024059107A1PGDB_A013617PGDB_C002827PGDB_AS000707View
2D structure for PGDB_C002833
% Degradation-=39.4%100 nM-IKZF1--WO2024059107A1PGDB_A013697PGDB_C002833PGDB_AS000707View
2D structure for PGDB_C002821
% Degradation-=97.7%100 nM-IKZF1--WO2024059107A1PGDB_A016752PGDB_C002821PGDB_AS000707View
2D structure for PGDB_C002812
% Degradation-=59.5%100 nM-IKZF1--WO2024059107A1PGDB_A019474PGDB_C002812PGDB_AS000707View
2D structure for PGDB_C002826
% Degradation-=98.6%100 nM-IKZF1--WO2024059107A1PGDB_A023879PGDB_C002826PGDB_AS000707View
2D structure for PGDB_C002835
% Degradation-=4.3%100 nM-IKZF1--WO2024059107A1PGDB_A024544PGDB_C002835PGDB_AS000707View
2D structure for PGDB_C002810
% Degradation-=62.1%100 nM-IKZF1--WO2024059107A1PGDB_A027536PGDB_C002810PGDB_AS000707View
2D structure for PGDB_C002844
% Degradation-=4.9%100 nM-IKZF1--WO2024059107A1PGDB_A028564PGDB_C002844PGDB_AS000707View
2D structure for PGDB_C002840
% Degradation-=12.3%100 nM-IKZF1--WO2024059107A1PGDB_A032074PGDB_C002840PGDB_AS000707View
2D structure for PGDB_C002806
% Degradation-=52.1%100 nM-IKZF1--WO2024059107A1PGDB_A032866PGDB_C002806PGDB_AS000707View
2D structure for PGDB_C002843
% Degradation-=6.7%100 nM-IKZF1--WO2024059107A1PGDB_A033140PGDB_C002843PGDB_AS000707View
2D structure for PGDB_C002808
% Degradation-=97.2%100 nM-IKZF1--WO2024059107A1PGDB_A033363PGDB_C002808PGDB_AS000707View
2D structure for PGDB_C002836
% Degradation-=10.7%100 nM-IKZF1--WO2024059107A1PGDB_A034704PGDB_C002836PGDB_AS000707View
2D structure for PGDB_C002846
% Degradation-=7.7%100 nM-IKZF1--WO2024059107A1PGDB_A036687PGDB_C002846PGDB_AS000707View
2D structure for PGDB_C002845
% Degradation-=8.7%100 nM-IKZF1--WO2024059107A1PGDB_A037908PGDB_C002845PGDB_AS000707View
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