Activity record

PGDB_A010274

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 = 14.3 nM

TargetGSPT1
Cell lineHL-60
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002047
PatentWO2023078410A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005327
Compound IDPGDB_C005327
Compound4-133;4-133
Source record IDPGDB_C005327
InChIKeyCJOGJAGFAWIFTH-JKGBFCRXSA-N

Assay context

Assay IDPGDB_AS002047
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineHL-60

Source evidence

Patent IDWO2023078410A1
Compound location

4-133;4-133

4-133;4-133 enlarged structure4-133;4-133 location on patent page 19
Activity table
Page 92 · table start
Page 93 · table end