Activity record

PGDB_A011319

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 53-60 %

TargetCRBN
E3 ligaseCRBN
Concentration0.5 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS002000
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000805
Compound IDPGDB_C000805
CompoundGT-09351
Source record IDPGDB_C000805
InChIKeyJXRKEBZJRUNWKF-KWRHIPAJSA-N

Assay context

Assay IDPGDB_AS002000
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration0.5 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120548310A
Compound location

GT-09351

GT-09351 enlarged structureGT-09351 location on patent page 26
Activity table
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