Assay

PGDB_AS002000

System: cell_basedTarget: CRBN
Assay context summary

Assay context

143 activity records
Assay familybiochemical
Systemcell_based
Readout% Inhibition
TargetCRBN
E3CRBN
TechnologyHTRF
Detection targetcell_inhibition
Activity compounds and values

Activity records

143 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C000853
% Inhibition-=10-20%0.5 uM-CRBNCRBN-CN120548310APGDB_A007060PGDB_C000853PGDB_AS002000View
2D structure for PGDB_C000939
% Inhibition-=40-53%0.5 uM-CRBNCRBN-CN120548310APGDB_A007158PGDB_C000939PGDB_AS002000View
2D structure for PGDB_C000854
% Inhibition-=10-20%0.5 uM-CRBNCRBN-CN120548310APGDB_A007926PGDB_C000854PGDB_AS002000View
2D structure for PGDB_C000829
% Inhibition-=40-53%0.5 uM-CRBNCRBN-CN120548310APGDB_A008317PGDB_C000829PGDB_AS002000View
2D structure for PGDB_C000982
% Inhibition-=20-30%0.5 uM-CRBNCRBN-CN120548310APGDB_A008960PGDB_C000982PGDB_AS002000View
2D structure for PGDB_C000749
% Inhibition-=10-20%0.5 uM-CRBNCRBN-CN120548310APGDB_A008962PGDB_C000749PGDB_AS002000View
2D structure for PGDB_C000967
% Inhibition-=30-40%0.5 uM-CRBNCRBN-CN120548310APGDB_A009289PGDB_C000967PGDB_AS002000View
2D structure for PGDB_C000984
% Inhibition-=30-40%0.5 uM-CRBNCRBN-CN120548310APGDB_A009613PGDB_C000984PGDB_AS002000View
2D structure for PGDB_C000940
% Inhibition-=30-40%0.5 uM-CRBNCRBN-CN120548310APGDB_A009618PGDB_C000940PGDB_AS002000View
2D structure for PGDB_C000947
% Inhibition-=20-30%0.5 uM-CRBNCRBN-CN120548310APGDB_A009985PGDB_C000947PGDB_AS002000View
2D structure for PGDB_C000911
% Inhibition-=20-30%0.5 uM-CRBNCRBN-CN120548310APGDB_A010008PGDB_C000911PGDB_AS002000View
2D structure for PGDB_C000957
% Inhibition-=20-30%0.5 uM-CRBNCRBN-CN120548310APGDB_A011230PGDB_C000957PGDB_AS002000View
2D structure for PGDB_C000837
% Inhibition-=53-60%0.5 uM-CRBNCRBN-CN120548310APGDB_A011283PGDB_C000837PGDB_AS002000View
2D structure for PGDB_C000805
% Inhibition-=53-60%0.5 uM-CRBNCRBN-CN120548310APGDB_A011319PGDB_C000805PGDB_AS002000View
2D structure for PGDB_C000973
% Inhibition-=30-40%0.5 uM-CRBNCRBN-CN120548310APGDB_A011371PGDB_C000973PGDB_AS002000View
2D structure for PGDB_C000833
% Inhibition-=30-40%0.5 uM-CRBNCRBN-CN120548310APGDB_A012842PGDB_C000833PGDB_AS002000View
2D structure for PGDB_C000859
% Inhibition-=30-40%0.5 uM-CRBNCRBN-CN120548310APGDB_A012844PGDB_C000859PGDB_AS002000View
2D structure for PGDB_C000840
% Inhibition-=40-53%0.5 uM-CRBNCRBN-CN120548310APGDB_A014285PGDB_C000840PGDB_AS002000View
2D structure for PGDB_C000938
% Inhibition-=53-60%0.5 uM-CRBNCRBN-CN120548310APGDB_A014330PGDB_C000938PGDB_AS002000View
2D structure for PGDB_C000948
% Inhibition-=30-40%0.5 uM-CRBNCRBN-CN120548310APGDB_A014374PGDB_C000948PGDB_AS002000View
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