Activity record

PGDB_A011864

Assay: % DegradationTarget: GSPT1QC: standardized
Activity overview

degradation = 30.46 %

TargetGSPT1
Cell lineNCI-H1155
ConcentrationConcentration context: 10 nM
Time6 h
Assay / ReadoutWestern_blot / % Degradation
Assay IDPGDB_AS000061
PatentWO2024125437A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C005363
Compound IDPGDB_C005363
Compound实施例 4
Source record IDPGDB_C005363
InChIKeyJNPQHBXSTIPACU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000061
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
TechnologyWestern_blot
ConcentrationConcentration context: 10 nM
Treatment time6 h
TargetGSPT1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDWO2024125437A1
Compound location

实施例 4

实施例 4 enlarged structure实施例 4 location on patent page 17
Activity table
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