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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A011985

Assay: % DegradationTarget: IKZF1QC: ambiguous

Activity overview

degradation = 75-100 %

TargetIKZF1

Cell lineNCI-H929

Concentration10 uM

Time24 h

Assay / ReadoutWestern_blot / % Degradation

Assay IDPGDB_AS001123

PatentWO2022146151A1

QC statusambiguous

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C009603

Compound1;1;1;1;1;1;1;1;1;1;Compound 1

Source record IDPGDB_C009598

InChIKeyQDSCVODHGXABJE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001123

Assay family% Degradation

Assay systemcell_based

Readout% Degradation

TechnologyWestern_blot

Concentration10 uM

Treatment time24 h

TargetIKZF1

E3Not specified

Cell lineNCI-H929

OrganismHomo sapiens

Source evidence

Patent IDWO2022146151A1

Compound location

1;1;1;1;1;1;1;1;1;1;Compound 1

1;1;1;1;1;1;1;1;1;1;Compound 1 enlarged structure

1;1;1;1;1;1;1;1;1;1;Compound 1 location on patent page 10

Activity table

Page 86 · table single

A patent-derived molecular glue bioactivity database with traceable evidence.

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0 countries/regions

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SIMM · NJU