Activity record

PGDB_A012014

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

IC50 = 333.25 nM

TargetCRBN
E3 ligaseCRBN
Time15 min
Assay / ReadoutHTRF / IC50
Assay IDPGDB_AS000570
PatentCN118852145A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001468
Compound IDPGDB_C001468
Compound实施例19
Source record IDPGDB_C001468
InChIKeyALDRQPBZUXNARS-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000570
Assay familybiochemical
Assay systembiochemical
ReadoutIC50
TechnologyHTRF
Treatment time15 min
TargetCRBN
E3CRBN
OrganismHomo sapiens

Source evidence

Patent IDCN118852145A
Compound location

实施例19

实施例19 enlarged structure实施例19 location on patent page 54
Activity table
Page 91 · table start
Page 92 · table end