Assay

PGDB_AS000570

System: biochemicalTarget: CRBN
Assay context summary

Assay context

19 activity records
Assay familybiochemical
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
OrganismHomo sapiens
TechnologyHTRF
Activity compounds and values

Activity records

19 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C001475
IC50-=316.86nM-—CRBNCRBN-CN118852145APGDB_A008335PGDB_C001475PGDB_AS000570View
2D structure for PGDB_C001468
IC50-=333.25nM-—CRBNCRBN-CN118852145APGDB_A012014PGDB_C001468PGDB_AS000570View
2D structure for PGDB_C001470
IC50-=322.59nM-—CRBNCRBN-CN118852145APGDB_A017444PGDB_C001470PGDB_AS000570View
2D structure for PGDB_C001484
IC50-=756.73nM-—CRBNCRBN-CN118852145APGDB_A017562PGDB_C001484PGDB_AS000570View
2D structure for PGDB_C001471
IC50-=119.97nM-—CRBNCRBN-CN118852145APGDB_A018386PGDB_C001471PGDB_AS000570View
2D structure for PGDB_C001456
IC50-=72.7nM-—CRBNCRBN-CN118852145APGDB_A023974PGDB_C001456PGDB_AS000570View
2D structure for PGDB_C001460
IC50-=246.58nM-—CRBNCRBN-CN118852145APGDB_A027509PGDB_C001460PGDB_AS000570View
2D structure for PGDB_C001458
IC50-=91.31nM-—CRBNCRBN-CN118852145APGDB_A037619PGDB_C001458PGDB_AS000570View
2D structure for PGDB_C001457
IC50-=65.68nM-—CRBNCRBN-CN118852145APGDB_A038266PGDB_C001457PGDB_AS000570View
2D structure for PGDB_C001477
IC50-=141.91nM-—CRBNCRBN-CN118852145APGDB_A041718PGDB_C001477PGDB_AS000570View
2D structure for PGDB_C001481
IC50-=476.53nM-—CRBNCRBN-CN118852145APGDB_A046085PGDB_C001481PGDB_AS000570View
2D structure for PGDB_C001465
IC50-=577.69nM-—CRBNCRBN-CN118852145APGDB_A054019PGDB_C001465PGDB_AS000570View
2D structure for PGDB_C001479
IC50-=281nM-—CRBNCRBN-CN118852145APGDB_A056396PGDB_C001479PGDB_AS000570View
2D structure for PGDB_C001483
IC50-=526.98nM-—CRBNCRBN-CN118852145APGDB_A056705PGDB_C001483PGDB_AS000570View
2D structure for PGDB_C001466
IC50-=172.31nM-—CRBNCRBN-CN118852145APGDB_A056875PGDB_C001466PGDB_AS000570View
2D structure for PGDB_C001474
IC50-=241.42nM-—CRBNCRBN-CN118852145APGDB_A062624PGDB_C001474PGDB_AS000570View
2D structure for PGDB_C001480
IC50-=102.37nM-—CRBNCRBN-CN118852145APGDB_A063972PGDB_C001480PGDB_AS000570View
2D structure for PGDB_C001459
IC50-=235.44nM-—CRBNCRBN-CN118852145APGDB_A068044PGDB_C001459PGDB_AS000570View
2D structure for PGDB_C001482
IC50-=468.11nM-—CRBNCRBN-CN118852145APGDB_A076571PGDB_C001482PGDB_AS000570View
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