Activity record

PGDB_A012299

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

IC50 > 500 nM

TargetCRBN
E3 ligaseCRBN
Time12 h
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001297
PatentWO2022219412A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001746
Compound IDPGDB_C001746
Compound34
Source record IDPGDB_C001745
InChIKeyZGCBBSXRJGIVRG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001297
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time12 h
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022219412A1
Compound location

34

34 enlarged structure34 location on patent page 111
Activity table
Page 167 · table start
Page 168 · table end