Assay

PGDB_AS001297

System: biochemicalTarget: CRBN
Assay context summary

Assay context

12 activity records
Assay familybinding
Systembiochemical
ReadoutIC50
TargetCRBN
E3CRBN
Technologyfluorescence
Activity compounds and values

Activity records

12 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C001746
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A012299PGDB_C001746PGDB_AS001297View
2D structure for PGDB_C001738
IC50->1700nM-—CRBNCRBN-WO2022219412A1PGDB_A015011PGDB_C001738PGDB_AS001297View
2D structure for PGDB_C001728
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A015604PGDB_C001728PGDB_AS001297View
2D structure for PGDB_C001736
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A020270PGDB_C001736PGDB_AS001297View
2D structure for PGDB_C001744
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A023690PGDB_C001744PGDB_AS001297View
2D structure for PGDB_C001740
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A028996PGDB_C001740PGDB_AS001297View
2D structure for PGDB_C001731
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A032736PGDB_C001731PGDB_AS001297View
2D structure for PGDB_C001742
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A033045PGDB_C001742PGDB_AS001297View
2D structure for PGDB_C001726
IC50->1100nM-—CRBNCRBN-WO2022219412A1PGDB_A053278PGDB_C001726PGDB_AS001297View
2D structure for PGDB_C001724
IC50-<=500nM-—CRBNCRBN-WO2022219412A1PGDB_A058784PGDB_C001724PGDB_AS001297View
2D structure for PGDB_C001729
IC50->1700nM-—CRBNCRBN-WO2022219412A1PGDB_A062687PGDB_C001729PGDB_AS001297View
2D structure for PGDB_C001733
IC50->500nM-—CRBNCRBN-WO2022219412A1PGDB_A076716PGDB_C001733PGDB_AS001297View
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