Activity record

PGDB_A012502

Assay: % DegradationTarget: IKZF4QC: ambiguous
Activity overview

Dmax = 11 %

TargetIKZF4
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS001833
PatentUS20250129061A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007373
Compound IDPGDB_C007373
CompoundComparative Compound B
Source record IDPGDB_C007373
InChIKeyVACYFJWFXFNBTI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001833
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Detection targetprotein_degradation
TargetIKZF4
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDUS20250129061A1
Compound location

Comparative Compound B

Comparative Compound B enlarged structureComparative Compound B location on patent page 76
Activity table
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