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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A012607

Assay: % DegradationTarget: IKZF1QC: standardized

Activity overview

DC50 = 0.047 nM

TargetIKZF1

E3 ligaseCRBN

Cell lineHT-1080

Time20 h

Assay / Readoutluminescence / DC50

Assay IDPGDB_AS001276

PatentWO2023025136A1

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C009985

Compound化合物 1;化合物 1

Source record IDPGDB_C009985

InChIKeyRIUZYGZRTWXCOM-AZKKKJBWSA-N

Assay context

Assay IDPGDB_AS001276

Assay family% Degradation

Assay systemcell_based

ReadoutDC50

Technologyluminescence

Treatment time20 h

TargetIKZF1

E3CRBN

Cell lineHT-1080

OrganismHomo sapiens

Source evidence

Patent IDWO2023025136A1

Compound location

化合物 1;化合物 1

化合物 1;化合物 1 enlarged structure

化合物 1;化合物 1 location on patent page 56

Activity table

Page 80 · table start

Page 81 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU