Activity record

PGDB_A012629

Assay: % DegradationTarget: IKZF3QC: ambiguous
Activity overview

DC50 > 6136 nM

TargetIKZF3
Cell lineJurkat
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS002122
PatentWO2025064197
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010132
Compound IDPGDB_C010132
CompoundEXAMPLE 3
Source record IDPGDB_C010132
InChIKeyGTORSYLSHANUNO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002122
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetIKZF3
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2025064197
Compound location

EXAMPLE 3

EXAMPLE 3 enlarged structureEXAMPLE 3 location on patent page 81
Activity table
Page 88 · table single