Activity record

PGDB_A012842

Assay: biochemicalTarget: CRBNQC: standardized
Activity overview

inhibition = 30-40 %

TargetCRBN
E3 ligaseCRBN
Concentration0.5 uM
Assay / ReadoutHTRF / % Inhibition
Assay IDPGDB_AS002000
PatentCN120548310A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000833
Compound IDPGDB_C000833
CompoundGT-09430
Source record IDPGDB_C000833
InChIKeyLAKZBOQUQMRXDO-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002000
Assay familybiochemical
Assay systemcell_based
Readout% Inhibition
TechnologyHTRF
Concentration0.5 uM
Detection targetcell_inhibition
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120548310A
Compound location

GT-09430

GT-09430 enlarged structureGT-09430 location on patent page 29
Activity table
Page 147 · table start
Page 148 · table end