Activity record

PGDB_A013177

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 < 1 uM

TargetCRBN
E3 ligaseCRBN
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001252
PatentWO2022066835A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C001422
Compound IDPGDB_C001422
Compound65;65
Source record IDPGDB_C001422
InChIKeyHVPWPWAEMGABDB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001252
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022066835A1
Compound location

65;65

65;65 enlarged structure65;65 location on patent page 185
Activity table
Page 165 · table single