Activity record

PGDB_A013253

Assay: % DegradationTarget: CCNKQC: ambiguous
Activity overview

DC50 < 10 nM

TargetCCNK
Cell lineHEK293T_Nluc_CCNK-tagged
Time4 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001249
PatentWO2025104236
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010872
Compound IDPGDB_C010872
Compound29;29
Source record IDPGDB_C010872
InChIKeyYUVBKFAHMZKEFJ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001249
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time4 h
TargetCCNK
E3Not specified
Cell lineHEK293T_Nluc_CCNK-tagged
OrganismHomo sapiens

Source evidence

Patent IDWO2025104236
Compound location

29;29

29;29 enlarged structure29;29 location on patent page 136
Activity table
Page 163 · table start
Page 164 · table end