PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2025104236

AssigneeProxygen

TitlePyrazole compounds as cullin ring ubiquitin ligase compounds

Family ID88837227

Family members1

Filing year2024

Publication date2025-05-22

JurisdictionWO

Compounds51

Activity records132

Assays3

Activity compounds and values

Activity records

132 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
EC50	-	=	0.1-1	uM	-	—	CCNK	-	Hs-578T	PGDB_A008011	PGDB_C010883	PGDB_AS000816	View
EC50	-	=	10-100	nM	-	—	CCNK	-	Hs-578T	PGDB_A008342	PGDB_C010849	PGDB_AS000816	View
EC50	-	=	10-100	nM	-	—	CCNK	-	Hs-578T	PGDB_A009913	PGDB_C010873	PGDB_AS000816	View
DC50	-	=	10-100	nM	-	—	CCNK	-	HEK293T_Nluc_CCNK-tagged	PGDB_A010593	PGDB_C010853	PGDB_AS001249	View
EC50	-	=	0.1-1	uM	-	—	CCNK	-	BT-474	PGDB_A010728	PGDB_C010858	PGDB_AS000468	View
EC50	-	=	0.1-1	uM	-	—	CCNK	-	Hs-578T	PGDB_A011653	PGDB_C010870	PGDB_AS000816	View
DC50	-	=	0.1-1	uM	-	—	CCNK	-	HEK293T_Nluc_CCNK-tagged	PGDB_A012115	PGDB_C010858	PGDB_AS001249	View
EC50	-	=	0.1-1	uM	-	—	CCNK	-	Hs-578T	PGDB_A012438	PGDB_C010861	PGDB_AS000816	View
DC50	-	<	10	nM	-	—	CCNK	-	HEK293T_Nluc_CCNK-tagged	PGDB_A013253	PGDB_C010872	PGDB_AS001249	View
EC50	-	=	1-100	uM	-	—	CCNK	-	BT-474	PGDB_A013981	PGDB_C010867	PGDB_AS000468	View
EC50	-	<	10	nM	-	—	CCNK	-	BT-474	PGDB_A014518	PGDB_C010851	PGDB_AS000468	View
EC50	-	=	10-100	nM	-	—	CCNK	-	Hs-578T	PGDB_A014883	PGDB_C010891	PGDB_AS000816	View
DC50	-	=	1-100	uM	-	—	CCNK	-	HEK293T_Nluc_CCNK-tagged	PGDB_A015420	PGDB_C010889	PGDB_AS001249	View
DC50	-	=	0.1-1	uM	-	—	CCNK	-	HEK293T_Nluc_CCNK-tagged	PGDB_A015677	PGDB_C010862	PGDB_AS001249	View
DC50	-	=	0.1-1	uM	-	—	CCNK	-	HEK293T_Nluc_CCNK-tagged	PGDB_A015770	PGDB_C010885	PGDB_AS001249	View
EC50	-	=	1-100	uM	-	—	CCNK	-	Hs-578T	PGDB_A015874	PGDB_C010855	PGDB_AS000816	View
EC50	-	=	1-100	uM	-	—	CCNK	-	Hs-578T	PGDB_A016141	PGDB_C010889	PGDB_AS000816	View
EC50	-	=	1-100	uM	-	—	CCNK	-	BT-474	PGDB_A018119	PGDB_C010844	PGDB_AS000468	View
EC50	-	=	10-100	nM	-	—	CCNK	-	Hs-578T	PGDB_A018781	PGDB_C010878	PGDB_AS000816	View
EC50	-	=	0.1-1	uM	-	—	CCNK	-	Hs-578T	PGDB_A019171	PGDB_C010880	PGDB_AS000816	View

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