Activity record

PGDB_A013315

Assay: viabilityTarget: CDK12QC: ambiguous
Activity overview

IC50 = 2861 nM

TargetCDK12
Cell lineMDA-MB-231
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001069
PatentCN121108130A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C007327
Compound IDPGDB_C007327
Compound实施例3;实施例3
Source record IDPGDB_C007327
InChIKeyCSBDVLWNGTUYQC-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001069
Assay familyviability
Assay systemcell_based
ReadoutIC50
TargetCDK12
E3Not specified
Cell lineMDA-MB-231
OrganismHomo sapiens

Source evidence

Patent IDCN121108130A
Compound location

实施例3;实施例3

实施例3;实施例3 enlarged structure实施例3;实施例3 location on patent page 22
Activity table
Page 36 · table single