Assay

PGDB_AS001069

System: cell_basedCell line: MDA-MB-231
Assay context summary

Assay context

12 activity records
Assay familyviability
Systemcell_based
ReadoutIC50
E3Not specified
Cell lineMDA-MB-231
OrganismHomo sapiens
Activity compounds and values

Activity records

12 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C007331
IC50-=30.35nM-—CDK12-MDA-MB-231CN121108130APGDB_A008061PGDB_C007331PGDB_AS001069View
2D structure for PGDB_C007327
IC50-=2861nM-—CDK12-MDA-MB-231CN121108130APGDB_A013315PGDB_C007327PGDB_AS001069View
2D structure for PGDB_C007329
IC50-=351.6nM-—CDK12-MDA-MB-231CN121108130APGDB_A031323PGDB_C007329PGDB_AS001069View
2D structure for PGDB_C007335
IC50-=219nM-—CDK12-MDA-MB-231CN121108130APGDB_A033466PGDB_C007335PGDB_AS001069View
2D structure for PGDB_C007333
IC50-=2925nM-—CDK12-MDA-MB-231CN121108130APGDB_A035112PGDB_C007333PGDB_AS001069View
2D structure for PGDB_C007326
IC50-=46.44nM-—CDK12-MDA-MB-231CN121108130APGDB_A040486PGDB_C007326PGDB_AS001069View
2D structure for PGDB_C007334
IC50-=120.5nM-—CDK12-MDA-MB-231CN121108130APGDB_A053429PGDB_C007334PGDB_AS001069View
2D structure for PGDB_C007325
IC50-=14.29nM-—CDK12-MDA-MB-231CN121108130APGDB_A058463PGDB_C007325PGDB_AS001069View
2D structure for PGDB_C007164
IC50-=20.75nM-—CDK12-MDA-MB-231CN121108130APGDB_A067450PGDB_C007164PGDB_AS001069View
2D structure for PGDB_C007332
IC50-=131.2nM-—CDK12-MDA-MB-231CN121108130APGDB_A070704PGDB_C007332PGDB_AS001069View
2D structure for PGDB_C007328
IC50-=125.6nM-—CDK12-MDA-MB-231CN121108130APGDB_A074027PGDB_C007328PGDB_AS001069View
2D structure for PGDB_C007330
IC50-=75.89nM-—CDK12-MDA-MB-231CN121108130APGDB_A074738PGDB_C007330PGDB_AS001069View
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