Activity record

PGDB_A013546

Assay: bindingTarget: CRBNQC: standardized
Activity overview

IC50 < 1 uM

TargetCRBN
E3 ligaseCRBN
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS001252
PatentWO2022066835A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C019592
Compound IDPGDB_C019592
Compound100;100
Source record IDPGDB_C001453
InChIKeyCBGRGVYIMBGCPT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001252
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2022066835A1
Compound location

100;100

100;100 enlarged structure100;100 location on patent page 194
Activity table
Page 165 · table single