Activity record

PGDB_A014222

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.15 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000522
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008116
Compound IDPGDB_C008116
Compound186;186;186
Source record IDPGDB_C008116
InChIKeyLMEUYTIRDNORQH-ODOQXGPZSA-N

Assay context

Assay IDPGDB_AS000522
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

186;186;186

186;186;186 enlarged structure186;186;186 location on patent page 48
Activity table
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Page 530 · table middle
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Page 532 · table end