Activity record

PGDB_A014548

Assay: % DegradationTarget: CDK12QC: ambiguous
Activity overview

IC50 <= 0.1 uM

TargetCDK12
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS002095
PatentWO2025110815A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010971
Compound IDPGDB_C010971
Compound88
Source record IDPGDB_C010971
InChIKeyHZZCZUFPOSEICA-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002095
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
TargetCDK12
E3Not specified

Source evidence

Patent IDWO2025110815A1
Compound location

88

88 enlarged structure88 location on patent page 122
Activity table
Page 145 · table start
Page 146 · table middle
Page 147 · table end