Activity record

PGDB_A014707

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

GI50 = 4.5 nM

TargetGSPT1
Cell lineNB4
Time72 h
Assay / Readoutluminescence / GI50
Assay IDPGDB_AS001086
PatentWO2024222614A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003184
Compound IDPGDB_C003184
Compound10;10;10;10
Source record IDPGDB_C003184
InChIKeyBUCYFPKLVBVFPY-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001086
Assay familyviability
Assay systemcell_based
ReadoutGI50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNB4

Source evidence

Patent IDWO2024222614A1
Compound location

10;10;10;10

10;10;10;10 enlarged structure10;10;10;10 location on patent page 11
Activity table
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