Activity record

PGDB_A014897

Assay: % DegradationTarget: IKZF2QC: ambiguous
Activity overview

Dmax = 74 %

TargetIKZF2
Time13 d
Assay / Readoutflow_cytometry / Dmax
Assay IDPGDB_AS001641
PatentWO2025049840
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C010126
Compound IDPGDB_C010126
Compound2
Source record IDPGDB_C010126
InChIKeyKLWWIJBBBDWGRY-VNHLFDKOSA-N

Assay context

Assay IDPGDB_AS001641
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyflow_cytometry
Treatment time13 d
Detection targetprotein_degradation
TargetIKZF2
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025049840
Compound location

2

2 enlarged structure2 location on patent page 85
Activity table
Page 108 · table single