Activity record

PGDB_A014942

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax > 75 %

TargetNEK7
E3 ligaseCRBN
Assay / ReadoutDmax / % Degradation
Assay IDPGDB_AS002165
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020430
Compound IDPGDB_C020430
Compound257.0
Source record IDPGDB_C016560
InChIKeyLLZXADXOKPOHET-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002165
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TargetNEK7
E3CRBN

Source evidence

Patent IDWO2025024521A1
Compound location

257.0

257.0 enlarged structure257.0 location on patent page 87
Activity table
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