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SIMM · NJU

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A patent-derived molecular glue bioactivity database with traceable evidence.

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SIMM · NJU

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SIMM · NJU

Activity record

PGDB_A015154

Assay: % DegradationTarget: WEE1QC: standardized

Activity overview

degradation = 0-20 %

TargetWEE1

ConcentrationConcentration series: 500 nM, 50 nM

Time24 h

Assay / ReadoutWestern_blot / percent_remaining

Assay IDPGDB_AS001655

PatentCN120548310A

QC statusstandardized

Evidence details

Compound, assay context, and source

Compound

Compound IDPGDB_C000782

CompoundGT-05335

Source record IDPGDB_C000782

InChIKeyNIAOEYFIMYQKCG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001655

Assay family% Degradation

Assay systemcell_based

Readoutpercent_remaining

TechnologyWestern_blot

ConcentrationConcentration series: 500 nM, 50 nM

Treatment time24 h

Detection targetprotein_degradation

TargetWEE1

E3Not specified

OrganismHomo sapiens

Source evidence

Patent IDCN120548310A

Compound location

GT-05335

GT-05335 enlarged structure

GT-05335 location on patent page 46

Activity table

Page 140 · table start

Page 141 · table middle

Page 142 · table middle

Page 143 · table middle

Page 144 · table middle

Page 145 · table end

A patent-derived molecular glue bioactivity database with traceable evidence.

Global reach

0

0 countries/regions

·

SIMM · NJU