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Compound
PGDB_C000782
7 activity records1 related patents
2D structure
CC1(C)CCC(C(=O)N2CCN(C3CCN(Cc4ccc5c(c4)CN(N4CCC(=O)NC4=O)C5=O)CC3(F)F)CC2)=C(c2ccc(Cl)cc2)C1Compound summary
Physicochemical properties
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| IC50 | - | = | 1.5-1.9 | uM | - | — | CRBN | CRBN | - | CN120548310A | PGDB_A008015 | PGDB_C000782 | PGDB_AS000323 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF3 | - | - | CN120548310A | PGDB_A009596 | PGDB_C000782 | PGDB_AS000102 | View |
| % Degradation | - | >= | 20 | % | Concentration series: 500 nM, 50 nM | 24 h | GSPT1 | - | - | CN120548310A | PGDB_A012594 | PGDB_C000782 | PGDB_AS001466 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | WEE1 | - | - | CN120548310A | PGDB_A015154 | PGDB_C000782 | PGDB_AS001655 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF1 | - | - | CN120548310A | PGDB_A042183 | PGDB_C000782 | PGDB_AS000946 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | CSNK1A1 | - | - | CN120548310A | PGDB_A053766 | PGDB_C000782 | PGDB_AS001449 | View |
| % Degradation | - | = | 0-20 | % | Concentration series: 500 nM, 50 nM | 24 h | IKZF2 | - | - | CN120548310A | PGDB_A073405 | PGDB_C000782 | PGDB_AS002025 | View |