Activity record

PGDB_A015288

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Kd = 0.088 uM

TargetCRBN
E3 ligaseCRBN
Assay / ReadoutKd / binding
Assay IDPGDB_AS000522
PatentWO2025043225
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C008071
Compound IDPGDB_C008071
Compound141;141;141
Source record IDPGDB_C008071
InChIKeyJNBWRAGDPQXHOG-XYPWUTKMSA-N

Assay context

Assay IDPGDB_AS000522
Assay familybinding
Assay systembiochemical
ReadoutKd
TargetCRBN
E3CRBN

Source evidence

Patent IDWO2025043225
Compound location

141;141;141

141;141;141 enlarged structure141;141;141 location on patent page 43
Activity table
Page 529 · table start
Page 530 · table middle
Page 531 · table middle
Page 532 · table end