Activity record

PGDB_A015909

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

DC50 = 6 nM

TargetNEK7
Cell lineCAL-51
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001365
PatentWO2025024521A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C020435
Compound IDPGDB_C020435
Compound89
Source record IDPGDB_C020262
InChIKeyLCRRQHKUCAPQRM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001365
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2025024521A1
Activity table
Page 414 · table start
Page 415 · table middle
Page 416 · table end