PatGlueDB | Molecular Glue Patent Bioactivity Database

Assay context summary

Assay context

282 activity records

Assay family% Degradation

Systemcell_based

ReadoutDC50

TargetNEK7

E3Not specified

Cell lineCAL-51

OrganismHomo sapiens

Technologyluminescence

Activity compounds and values

Activity records

282 records

Metric	Control	Relation	Value	Unit	Concentration	Time	Target	E3	Cell line	Patent	Record ID	Compound	Assay	Details
DC50	-	=	7	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007017	PGDB_C020374	PGDB_AS001365	View
DC50	-	=	50	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007058	PGDB_C020270	PGDB_AS001365	View
DC50	-	=	1	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007128	PGDB_C020382	PGDB_AS001365	View
DC50	-	=	3	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007150	PGDB_C020440	PGDB_AS001365	View
DC50	-	=	26	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007433	PGDB_C020455	PGDB_AS001365	View
DC50	-	=	345	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007549	PGDB_C020381	PGDB_AS001365	View
DC50	-	=	21	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007564	PGDB_C020259	PGDB_AS001365	View
DC50	-	=	0.4	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007662	PGDB_C020437	PGDB_AS001365	View
DC50	-	=	4	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007836	PGDB_C010388	PGDB_AS001365	View
DC50	-	=	1	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A007851	PGDB_C020440	PGDB_AS001365	View
DC50	-	=	3	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A008322	PGDB_C011097	PGDB_AS001365	View
DC50	-	=	4	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A008591	PGDB_C020431	PGDB_AS001365	View
DC50	-	=	28	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A009139	PGDB_C020207	PGDB_AS001365	View
DC50	-	=	7	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A010578	PGDB_C020256	PGDB_AS001365	View
DC50	-	=	1	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A010685	PGDB_C020378	PGDB_AS001365	View
DC50	-	=	47	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A010758	PGDB_C020338	PGDB_AS001365	View
DC50	-	=	1	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A011182	PGDB_C020200	PGDB_AS001365	View
DC50	-	=	14	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A011214	PGDB_C020313	PGDB_AS001365	View
DC50	-	=	51	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A011259	PGDB_C020290	PGDB_AS001365	View
DC50	-	=	8	nM	-	—	NEK7	-	CAL-51	WO2025024521A1	PGDB_A011330	PGDB_C020213	PGDB_AS001365	View

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